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Dissecting the effects of METTL3 on alternative splicing in prostate cancer

Although the role of METTL3 has been extensively studied in many cancers, its role in isoform switching in prostate cancer (PCa) has been poorly explored. To investigate its role, we applied standard RNA-sequencing and long-read direct RNA-sequencing from Oxford Nanopore to examine how METTL3 affect...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Shi, Ling, Liang, Yonghao, Ng, Judy Kin-Wing, Yin, Chan Hoi, Wang, Lingyi, Hou, Jinpao, Wang, Yiwei, Fung, Cathy Sin-Hang, Chiu, Peter Ka-Fung, Ng, Chi-Fai, Tsui, Stephen Kwok-Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477979/
https://www.ncbi.nlm.nih.gov/pubmed/37675218
http://dx.doi.org/10.3389/fonc.2023.1227016