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Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies

Currently, immune checkpoint inhibitors (ICIs) are widely considered the standard initial treatment for advanced non-small cell lung cancer (NSCLC) when there are no targetable driver oncogenic alternations. NSCLC tumors that have two alterations in tumor suppressor genes, such as liver kinase B1 (L...

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Detalles Bibliográficos
Autores principales: Tanaka, Ichidai, Koyama, Junji, Itoigawa, Hideyuki, Hayai, Shunsaku, Morise, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477992/
https://www.ncbi.nlm.nih.gov/pubmed/37675220
http://dx.doi.org/10.3389/fonc.2023.1249237