A nuclear orthologue of the dNTP triphosphohydrolase SAMHD1 controls dNTP homeostasis and genomic stability in Trypanosoma brucei

Maintenance of dNTPs pools in Trypanosoma brucei is dependent on both biosynthetic and degradation pathways that together ensure correct cellular homeostasis throughout the cell cycle which is essential for the preservation of genomic stability. Both the salvage and de novo pathways participate in t...

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Detalles Bibliográficos
Autores principales: Antequera-Parrilla, Pablo, Castillo-Acosta, Víctor M., Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, González-Pacanowska, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478004/
https://www.ncbi.nlm.nih.gov/pubmed/37674581
http://dx.doi.org/10.3389/fcimb.2023.1241305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478004/
https://www.ncbi.nlm.nih.gov/pubmed/37674581
http://dx.doi.org/10.3389/fcimb.2023.1241305

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