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Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps

INTRODUCTION: Neutrophil granulocytes predominate in the lungs of patients infected with Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection, neutrophils release neutrophil extracellular traps (NETs), an antimicrobial mechanism by which a DNA-backbone spiked with anti...

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Detalles Bibliográficos
Autores principales: García-Bengoa, María, Meurer, Marita, Stehr, Matthias, Elamin, Ayssar A., Singh, Mahavir, Oehlmann, Wulf, Mörgelin, Matthias, von Köckritz-Blickwede, Maren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478095/
https://www.ncbi.nlm.nih.gov/pubmed/37675111
http://dx.doi.org/10.3389/fimmu.2023.1206529