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A scalable human iPSC-based neuromuscular disease model on suspended biobased elastomer nanofiber scaffolds

Many devastating neuromuscular diseases currently lack effective treatments. This is in part due to a lack of drug discovery platforms capable of assessing complex human neuromuscular disease phenotypes in a scalable manner. A major obstacle has been generating scaffolds to stabilise mature contract...

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Detalles Bibliográficos
Autores principales: Cheesbrough, Aimee, Harley, Peter, Riccio, Federica, Wu, Lei, Song, Wenhui, Lieberam, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOP Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478173/
https://www.ncbi.nlm.nih.gov/pubmed/37619554
http://dx.doi.org/10.1088/1758-5090/acf39e