Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients

BACKGROUND: Monogenetic inborn errors of metabolism cause a wide phenotypic heterogeneity that may even differ between family members carrying the same genetic variant. Computational modelling of metabolic networks may identify putative sources of this inter-patient heterogeneity. Here, we mainly fo...

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Detalles Bibliográficos
Autores principales: Odendaal, Christoff, Jager, Emmalie A., Martines, Anne-Claire M. F., Vieira-Lara, Marcel A., Huijkman, Nicolette C. A., Kiyuna, Ligia A., Gerding, Albert, Wolters, Justina C., Heiner-Fokkema, Rebecca, van Eunen, Karen, Derks, Terry G. J., Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478272/
https://www.ncbi.nlm.nih.gov/pubmed/37667308
http://dx.doi.org/10.1186/s12915-023-01652-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478272/
https://www.ncbi.nlm.nih.gov/pubmed/37667308
http://dx.doi.org/10.1186/s12915-023-01652-9

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