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BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6

BACKGROUND: The tumor microenvironment (TME) is a supportive environment responsible for promoting the growth and proliferation of tumor cells. Current studies have revealed that the bone marrow mesenchymal stem cells (BM-MSCs), a type of crucial stromal cells in the TME, can promote the malignant p...

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Detalles Bibliográficos
Autores principales: Pan, Chengyun, Hu, Tianzhen, Liu, Ping, Ma, Dan, Cao, Shuyun, Shang, Qin, Zhang, Luxin, Chen, Qingzhen, Fang, Qin, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478283/
https://www.ncbi.nlm.nih.gov/pubmed/37670388
http://dx.doi.org/10.1186/s12967-023-04464-1