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Establishment of a large-scale patient-derived high-risk colorectal adenoma organoid biobank for high-throughput and high-content drug screening

BACKGROUND: Colorectal adenoma (CA), especially high-risk CA (HRCA), is a precancerous lesion with high prevalence and recurrence rate and accounts for about 90% incidence of sporadic colorectal cancer cases worldwide. Currently, recurrent CA can only be treated with repeated invasive polypectomies,...

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Detalles Bibliográficos
Autores principales: Luo, Zhongguang, Wang, Bangting, Luo, Feifei, Guo, Yumeng, Jiang, Ning, Wei, Jinsong, Wang, Xin, Tseng, Yujen, Chen, Jian, Zhao, Bing, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478412/
https://www.ncbi.nlm.nih.gov/pubmed/37667332
http://dx.doi.org/10.1186/s12916-023-03034-y