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Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to respiratory failure. Many preclinical studies have investigated the therapeutic potential of stem cell-derived exos...

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Detalles Bibliográficos
Autores principales: Liu, Qun, Bi, Youkun, Song, Shaole, Zhu, Keqi, Qiao, Xinlong, Wang, Huiwen, Ji, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478444/
https://www.ncbi.nlm.nih.gov/pubmed/37667335
http://dx.doi.org/10.1186/s13287-023-03449-7