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Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis

BACKGROUND: Lumbar facet joint osteoarthritis (LFJ OA) is a common disease, and there is still a lack of effective disease-modifying therapies. Our aim was to determine the therapeutic effect of hypoxia-treated adipose mesenchymal stem cell (ADSC)-derived exosomes (Hypo-ADSC-Exos) on the protective...

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Detalles Bibliográficos
Autores principales: Zhao, Jinyun, Sun, Yi, Sheng, Xiaolong, Xu, Jiaqi, Dai, Guoyu, He, Rundong, Jin, Yuxin, Liu, Zhide, Xie, Yong, Wu, Tianding, Cao, Yong, Hu, Jianzhong, Duan, Chunyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478461/
https://www.ncbi.nlm.nih.gov/pubmed/37670256
http://dx.doi.org/10.1186/s10020-023-00709-3