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HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases

HMGB1, a nucleoprotein, is expressed in almost all eukaryotic cells. During cell activation and cell death, HMGB1 can function as an alarm protein (alarmin) or damage-associated molecular pattern (DAMP) and mediate early inflammatory and immune response when it is translocated to the extracellular s...

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Detalles Bibliográficos
Autores principales: Ren, Wenxuan, Zhao, Lei, Sun, Ying, Wang, Xichang, Shi, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478470/
https://www.ncbi.nlm.nih.gov/pubmed/37667233
http://dx.doi.org/10.1186/s10020-023-00717-3