Exendin-4 ameliorates tau hyperphosphorylation and cognitive impairment in type 2 diabetes through acting on Wnt/β-catenin/NeuroD1 pathway

BACKGROUND:  Type 2 diabetes (T2D) is an independent risk factor for Alzheimer's disease (AD). Exendin-4 (Ex-4), a widely used glucagon-like peptide-1 receptor agonist drug in the treatment of T2D, has been demonstrated the therapeutic effects on diabetic encephalopathy (DE). Especially, the Ex...

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Detalles Bibliográficos
Autores principales: Kang, Xiaonan, Wang, Dan, Zhang, Lu, Huang, Teng, Liu, Siyue, Feng, Xiaohui, Guo, Yaoyao, Zhang, Ziyin, Wang, Zhongjing, Ren, Huihui, Yuan, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478475/
https://www.ncbi.nlm.nih.gov/pubmed/37667187
http://dx.doi.org/10.1186/s10020-023-00718-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478475/
https://www.ncbi.nlm.nih.gov/pubmed/37667187
http://dx.doi.org/10.1186/s10020-023-00718-2

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