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Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells

BACKGROUND: Our recent studies have demonstrated the crucial involvement of FOXA2 in the development of human pancreas. Reduction of FOXA2 expression during the differentiation of induced pluripotent stem cells (iPSCs) into pancreatic islets has been found to reduce α-and β-cell masses. However, the...

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Detalles Bibliográficos
Autores principales: Elsayed, Ahmed K., Alajez, Nehad M., Abdelalim, Essam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478503/
https://www.ncbi.nlm.nih.gov/pubmed/37670346
http://dx.doi.org/10.1186/s12964-023-01212-2