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Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII

A range of 3H-1,2-benzoxaphosphepine 2-oxide aryl derivatives with various substitution patterns at positions 7, 8, or 9 of the scaffold was synthesised in five steps from the commercially available salicylaldehydes. All of the newly obtained compounds were studied for their inhibition potency again...

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Detalles Bibliográficos
Autores principales: Balašova, Anastasija, Pustenko, Aleksandrs, Nocentini, Alessio, Vullo, Daniela, Supuran, Claudiu T., Žalubovskis, Raivis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478600/
https://www.ncbi.nlm.nih.gov/pubmed/37655449
http://dx.doi.org/10.1080/14756366.2023.2249267