Degradation of helicase-like transcription factor (HLTF) by β-TrCP promotes hepatocarcinogenesis via activation of the p62/mTOR axis

Helicase-like transcription factor (HLTF) has been found to be involved in the maintenance of genome stability and tumour suppression, but whether its downregulation in cancers is associated with posttranslational regulation remains unclear. Here, we observed that HLTF was significantly downregulate...

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Detalles Bibliográficos
Autores principales: Tan, Ye, Wu, Di, Liu, Ze-Yu, Yu, Hong-Qiang, Zheng, Xiang-Ru, Lin, Xiao-Tong, Bie, Ping, Zhang, Lei-Da, Xie, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478628/
https://www.ncbi.nlm.nih.gov/pubmed/36822623
http://dx.doi.org/10.1093/jmcb/mjad012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478628/
https://www.ncbi.nlm.nih.gov/pubmed/36822623
http://dx.doi.org/10.1093/jmcb/mjad012

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