Design, synthesis, biological evaluation and molecular docking study of novel pleuromutilin derivatives containing substituted benzoxazole as antibacterial agents

A series of pleuromutilin analogs containing substituted benzoxazole were designed, synthesised, and assessed for their antibacterial activity both in vivo and in vitro. The MIC of the synthesised derivatives was initially assessed using the broth dilution method against four strains of Staphylococc...

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Detalles Bibliográficos
Autores principales: Ren, Jie, Zhang, Qi-Wen, He, Xian-Jin, Chen, Xiao-Ying, Zhou, Zi-Dan, Zeng, Zhen-Ling, Jin, Zhen, Tang, You-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478630/
https://www.ncbi.nlm.nih.gov/pubmed/37664987
http://dx.doi.org/10.1080/14756366.2023.2251712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478630/
https://www.ncbi.nlm.nih.gov/pubmed/37664987
http://dx.doi.org/10.1080/14756366.2023.2251712

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