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NHWD-870 protects the kidney from ischemia/reperfusion injury by upregulating the PI3K/AKT signaling pathway (experimental study)

Renal ischemia-reperfusion injury is a critical clinical condition with a potentially fatal prognosis if not adequately managed. NHWD-870, a known Brd4 inhibitor with anti-cancer properties, exhibits additional attributes such as antioxidant, anti-inflammatory, and anti-apoptotic effects, suggesting...

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Detalles Bibliográficos
Autores principales: Younis, Saba Sahib, Ghafil, Fadhaa Abdul Ameer, Majeed, Sahar, Hadi, Najah Rayish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478670/
https://www.ncbi.nlm.nih.gov/pubmed/37675155
http://dx.doi.org/10.25122/jml-2022-0309