Impaired proliferation and migration of HUVEC and melanoma cells by human anti-FGF2 mAbs derived from a murine hybridoma by guided selection

Disadvantages of using murine monoclonal antibodies (mAb) in human therapy, such as immunogenicity response, led to the development of technologies to transform murine antibodies into human antibodies. The murine anti-FGF2 3F12E7 mAb was proposed as a promising agent to treat metastatic melanoma tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Georg Magalhães, Carolina, Ploeger Mansueli, Carla, Manieri, Tânia Maria, Quintilio, Wagner, Garbuio, Angélica, de Jesus Marinho, Juan, de Moraes, Jane Zveiter, Tsuruta, Lilian Rumi, Moro, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478743/
https://www.ncbi.nlm.nih.gov/pubmed/37661761
http://dx.doi.org/10.1080/21655979.2023.2252667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478743/
https://www.ncbi.nlm.nih.gov/pubmed/37661761
http://dx.doi.org/10.1080/21655979.2023.2252667

Ejemplares similares