Single-cell Profiling Uncovers a Muc4-Expressing Metaplastic Gastric Cell Type Sustained by Helicobacter pylori-driven Inflammation

Mechanisms for Helicobacter pylori (Hp)-driven stomach cancer are not fully understood. In a transgenic mouse model of gastric preneoplasia, concomitant Hp infection and induction of constitutively active KRAS (Hp+KRAS+) alters metaplasia phenotypes and elicits greater inflammation than either pertu...

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Detalles Bibliográficos
Autores principales: O'Brien, Valerie P., Kang, Yuqi, Shenoy, Meera K., Finak, Greg, Young, William C., Dubrulle, Julien, Koch, Lisa, Rodriguez Martinez, Armando E., Williams, Jeffery, Donato, Elizabeth, Batra, Surinder K., Yeung, Cecilia C.S., Grady, William M., Koch, Meghan A., Gottardo, Raphael, Salama, Nina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478791/
https://www.ncbi.nlm.nih.gov/pubmed/37674528
http://dx.doi.org/10.1158/2767-9764.CRC-23-0142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478791/
https://www.ncbi.nlm.nih.gov/pubmed/37674528
http://dx.doi.org/10.1158/2767-9764.CRC-23-0142

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