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Contributions of the N-terminal flanking residues of an antigenic peptide from the Japanese cedar pollen allergen Cry j 1 to the T-cell activation by HLA-DP5

Cry j 1 is a major allergen present in Japanese cedar (Cryptomeria japonica) pollens. Peptides with the core sequence of KVTVAFNQF from Cry j 1 (‘pCj1’) bind to HLA-DP5 and activate Th2 cells. In this study, we noticed that Ser and Lys at positions −2 and −3, respectively, in the N-terminal flanking...

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Detalles Bibliográficos
Autores principales: Kusano, Seisuke, Ueda, Sho, Oryoji, Daisuke, Toyoumi, Aya, Hashimoto-Tane, Akiko, Kishi, Hiroyuki, Hamana, Hiroshi, Muraguchi, Atsushi, Jin, Hui, Arase, Hisashi, Miyadera, Hiroko, Kishikawa, Reiko, Yoshikai, Yasunobu, Yamada, Hisakata, Yamamoto, Ken, Nishimura, Yasuharu, Saito, Takashi, Sasazuki, Takehiko, Yokoyama, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478803/
https://www.ncbi.nlm.nih.gov/pubmed/37418020
http://dx.doi.org/10.1093/intimm/dxad024