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Contributions of the N-terminal flanking residues of an antigenic peptide from the Japanese cedar pollen allergen Cry j 1 to the T-cell activation by HLA-DP5
Cry j 1 is a major allergen present in Japanese cedar (Cryptomeria japonica) pollens. Peptides with the core sequence of KVTVAFNQF from Cry j 1 (‘pCj1’) bind to HLA-DP5 and activate Th2 cells. In this study, we noticed that Ser and Lys at positions −2 and −3, respectively, in the N-terminal flanking...
Autores principales: | Kusano, Seisuke, Ueda, Sho, Oryoji, Daisuke, Toyoumi, Aya, Hashimoto-Tane, Akiko, Kishi, Hiroyuki, Hamana, Hiroshi, Muraguchi, Atsushi, Jin, Hui, Arase, Hisashi, Miyadera, Hiroko, Kishikawa, Reiko, Yoshikai, Yasunobu, Yamada, Hisakata, Yamamoto, Ken, Nishimura, Yasuharu, Saito, Takashi, Sasazuki, Takehiko, Yokoyama, Shigeyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478803/ https://www.ncbi.nlm.nih.gov/pubmed/37418020 http://dx.doi.org/10.1093/intimm/dxad024 |
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