Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy

Radiolabeled fibroblast activation protein (FAP) inhibitors (FAPIs) have shown promise as cancer diagnostic agents; however, the relatively short tumor retention of FAPIs may limit their application in radioligand therapy. In this paper, we report the design, synthesis, and evaluation of a FAPI tetr...

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Detalles Bibliográficos
Autores principales: Pang, Yizhen, Zhao, Liang, Fang, Jianyang, Chen, Jianhao, Meng, Lingxin, Sun, Long, Wu, Hua, Guo, Zhide, Lin, Qin, Chen, Haojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2023
Materias:
Basic Science Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478824/
https://www.ncbi.nlm.nih.gov/pubmed/37321827
http://dx.doi.org/10.2967/jnumed.123.265599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478824/
https://www.ncbi.nlm.nih.gov/pubmed/37321827
http://dx.doi.org/10.2967/jnumed.123.265599

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