Cargando…
Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy
Radiolabeled fibroblast activation protein (FAP) inhibitors (FAPIs) have shown promise as cancer diagnostic agents; however, the relatively short tumor retention of FAPIs may limit their application in radioligand therapy. In this paper, we report the design, synthesis, and evaluation of a FAPI tetr...
Autores principales: | Pang, Yizhen, Zhao, Liang, Fang, Jianyang, Chen, Jianhao, Meng, Lingxin, Sun, Long, Wu, Hua, Guo, Zhide, Lin, Qin, Chen, Haojun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Nuclear Medicine
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478824/ https://www.ncbi.nlm.nih.gov/pubmed/37321827 http://dx.doi.org/10.2967/jnumed.123.265599 |
Ejemplares similares
-
Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of (68)Ga-Labeled FAPI Dimer
por: Zhao, Liang, et al.
Publicado: (2022) -
Clinical Evaluation of (68)Ga-FAPI-RGD for Imaging of Fibroblast Activation Protein and Integrin α(v)β(3) in Various Cancer Types
por: Zhao, Liang, et al.
Publicado: (2023) -
Fibroblast Activation Protein-Targeted Radioligand Therapy with (177)Lu-EB-FAPI for Metastatic Radioiodine-Refractory Thyroid Cancer: First-in-Human, Dose-Escalation Study
por: Fu, Hao, et al.
Publicado: (2023) -
Subclass Analysis of Malignant, Inflammatory and Degenerative Pathologies Based on Multiple Timepoint FAPI-PET Acquisitions Using FAPI-02, FAPI-46 and FAPI-74
por: Glatting, Frederik M., et al.
Publicado: (2022) -
FAPI-04 Uptake in Healthy Tissues of Cancer Patients in (68)Ga-FAPI-04 PET/CT Imaging
por: Gündoğan, Cihan, et al.
Publicado: (2021)