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Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin

Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links F-actin to integrins. F-actin constantly moves on FAs, yet how Talin simultaneously maintains the connection to F-actin and transmits forces...

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Detalles Bibliográficos
Autores principales: Yamashiro, Sawako, Rutkowski, David M., Ann Lynch, Kelli, Liu, Ying, Vavylonis, Dimitrios, Watanabe, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479399/
https://www.ncbi.nlm.nih.gov/pubmed/37674715
http://dx.doi.org/10.21203/rs.3.rs-3254213/v1