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Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin
Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links F-actin to integrins. F-actin constantly moves on FAs, yet how Talin simultaneously maintains the connection to F-actin and transmits forces...
Autores principales: | Yamashiro, Sawako, Rutkowski, David M., Ann Lynch, Kelli, Liu, Ying, Vavylonis, Dimitrios, Watanabe, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479399/ https://www.ncbi.nlm.nih.gov/pubmed/37674715 http://dx.doi.org/10.21203/rs.3.rs-3254213/v1 |
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