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Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory transcriptional signature in young Pink1−/− rats
BACKGROUND: Parkinson disease (PD) is the fastest growing neurodegenerative disease. The molecular pathology of PD in the prodromal phase is poorly understood; as such, there are no specific prognostic or diagnostic tests. A validated Pink1 genetic knockout rat was used to model early-onset and prog...
Autores principales: | Lechner, Sarah A., Barnett, David G.S., Gammie, Stephen C., Kelm-Nelson, Cynthia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479403/ https://www.ncbi.nlm.nih.gov/pubmed/37674708 http://dx.doi.org/10.21203/rs.3.rs-3269607/v1 |
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