Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy

OBJECTIVE: This study assessed the efficacy of INV-202, a novel peripherally restricted cannabinoid type-1 receptor (CB1R) inverse agonist, in a streptozotocin-induced type-1 diabetes nephropathy mouse model. METHODS: Diabetes was induced in 8-week-old C57BL6/J male mice via intraperitoneal injectio...

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Detalles Bibliográficos
Autores principales: Jacquot, Laetitia, Pointeau, Océane, Roger-Villeboeuf, Célia, Passilly-Degrace, Patricia, Belkaid, Rim, Regazzoni, Isaline, Leemput, Julia, Buch, Chloé, Demizieux, Laurent, Vergès, Bruno, Degrace, Pascal, Crater, Glenn, Jourdan, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Nephrology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479578/
https://www.ncbi.nlm.nih.gov/pubmed/37675364
http://dx.doi.org/10.3389/fneph.2023.1138416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479578/
https://www.ncbi.nlm.nih.gov/pubmed/37675364
http://dx.doi.org/10.3389/fneph.2023.1138416

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