Cargando…

Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy

OBJECTIVE: This study assessed the efficacy of INV-202, a novel peripherally restricted cannabinoid type-1 receptor (CB1R) inverse agonist, in a streptozotocin-induced type-1 diabetes nephropathy mouse model. METHODS: Diabetes was induced in 8-week-old C57BL6/J male mice via intraperitoneal injectio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jacquot, Laetitia, Pointeau, Océane, Roger-Villeboeuf, Célia, Passilly-Degrace, Patricia, Belkaid, Rim, Regazzoni, Isaline, Leemput, Julia, Buch, Chloé, Demizieux, Laurent, Vergès, Bruno, Degrace, Pascal, Crater, Glenn, Jourdan, Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nephrology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479578/ https://www.ncbi.nlm.nih.gov/pubmed/37675364 http://dx.doi.org/10.3389/fneph.2023.1138416

Ejemplares similares

Orosensory Detection of Dietary Fatty Acids Is Altered in CB(1)R(−/−) Mice
por: Brissard, Léa, et al.
Publicado: (2018)

Endocannabinoids Produced by White Adipose Tissue Modulate Lipolysis in Lean but Not in Obese Rodent and Human
por: Buch, Chloé, et al.
Publicado: (2021)

Chemical Synthesis, Pharmacokinetic Properties and Biological Effects of JM-00266, a Putative Non-Brain Penetrant Cannabinoid Receptor 1 Inverse Agonist
por: Muller, Tania, et al.
Publicado: (2022)

CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice
por: Jourdan, Tony, et al.
Publicado: (2010)

Liraglutide reduces plasma dihydroceramide levels in patients with type 2 diabetes
por: Denimal, Damien, et al.
Publicado: (2023)

The Lipid-Sensor Candidates CD36 and GPR120 Are Differentially Regulated by Dietary Lipids in Mouse Taste Buds: Impact on Spontaneous Fat Preference
por: Martin, Céline, et al.
Publicado: (2011)

Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity
por: Martin, Céline, et al.
Publicado: (2012)

An Inconspicuous Offender: Apixaban-Induced Anticoagulant-Related Nephropathy
por: Shaw, Dylan J, et al.
Publicado: (2023)

Lupus nephropathy beyond immunosuppression: Searching for nephro and cardioprotection
por: Morales, Enrique, et al.
Publicado: (2023)

Treatment of membranous nephropathy: Perspectives on current and future therapies
por: Shah, Monarch, et al.
Publicado: (2023)

Bile Cast Nephropathy Secondary to Hemophagocytic Lymphohistiocytosis With Liver Failure
por: Chango Azanza, Juan Jose, et al.
Publicado: (2020)

IgA nephropathy: a review of existing and emerging therapies
por: Noor, Sahibzadi Mahrukh, et al.
Publicado: (2023)

Anticoagulant-Related Nephropathy: A Common, Under-Diagnosed Clinical Entity
por: Afiari, Agura, et al.
Publicado: (2022)

Urethral Amyloidosis in a Patient with IgA Nephropathy After Renal Transplant
por: Ojile, Nicholas, et al.
Publicado: (2017)

A Case Report of Generalized Pustular Psoriasis Associated With IgA Nephropathy
por: Klimko, Artsiom, et al.
Publicado: (2020)

Characterization of patients with IgA nephropathy with and without associated minimal change disease
por: Guo, Wei-yi, et al.
Publicado: (2023)

Chronic Nephropathy from Dietary Hyperoxaluria: Sustained Improvement of Renal Function after Dietary Intervention
por: Sun, Yijuan, et al.
Publicado: (2017)

Mechanism of Abelmoschus manihot L. in the Treatment of Contrast-Induced Nephropathy on the Basis of Network Pharmacology Analysis
por: Xu, Zhongchi, et al.
Publicado: (2022)

Case Report: Efficacy of albumin dialysis for the reversal of bile cast nephropathy-induced acute kidney injury
por: Issac, Aaron G., et al.
Publicado: (2023)

Author Correction: Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids
por: Besnard, Philippe, et al.
Publicado: (2018)

Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids
por: Besnard, Philippe, et al.
Publicado: (2018)

Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish
por: Li, Jia-Min, et al.
Publicado: (2018)

A Case of Purple Urine Bag Syndrome in a Spastic Partial Quadriplegic Male
por: Tul Llah, Sibghat, et al.
Publicado: (2016)

The epidemiology of hospitalised acute kidney injury not requiring dialysis in England from 1998 to 2013: retrospective analysis of hospital episode statistics
por: Kolhe, N. V., et al.
Publicado: (2016)

Hypertonicity: Pathophysiologic Concept and Experimental Studies
por: Argyropoulos, Christos, et al.
Publicado: (2016)

Comparing two models that reduce the number of nephrology fellowship positions in the United States
por: Desai, Tejas
Publicado: (2015)

Effect of telmisartan on kidney function in patients with chronic kidney disease: an observational study
por: Agrawal, Ashish, et al.
Publicado: (2016)

Hyperkalemia from Dietary Supplements
por: Batra, Vivek, et al.
Publicado: (2016)

Manifestations of Renal Impairment in Fructose-induced Metabolic Syndrome
por: Bratoeva, Kameliya, et al.
Publicado: (2017)

A Unique Case of Drug Interaction between Ticagrelor and Statin Leading to Acute Renal Failure
por: Samuel, Gbeminiyi, et al.
Publicado: (2017)

A Case Report of Fructosamine’s Unreliability as a Glycemic Control Assessment Tool in Nephrotic Syndrome
por: Senapathi, Sri HarshaVardhan, et al.
Publicado: (2017)

Predicting Quality of Life Changes in Hemodialysis Patients Using Machine Learning: Generation of an Early Warning System
por: Saadat, Shoab, et al.
Publicado: (2017)

Elevated serum osteoprotegerin may predict peripheral arterial disease after kidney transplantation: a single-center prospective cross-sectional study in Taiwan
por: Chen, Yen-Cheng, et al.
Publicado: (2017)

Unique Association of Multiple Seminal Vesicle Cysts with Contralateral Renal Agenesis: A Rare Variant of Zinner Syndrome
por: Khanduri, Sachin, et al.
Publicado: (2017)

Acute Renal Failure with Overdose of Labetalol: Special Considerations in Management
por: Guturu, Praveen
Publicado: (2017)

Severe Hyponatremia Presenting with Minimal Symptoms
por: Lwanga, Anita, et al.
Publicado: (2017)

Simultaneous Clinical Presentation of Renal Cell Carcinoma and Immunoglobulin Light Chain Amyloidosis
por: Prasad, Bhanu, et al.
Publicado: (2018)

Drug therapy and other factors associated with the development of acute kidney injury in critically ill patients: a cross-sectional study
por: Soares, Danielly Botelho, et al.
Publicado: (2018)

Diagnostic accuracy of Onen’s Alternative Grading System combined with Doppler evaluation of ureteral jets as an alternative in the diagnosis of obstructive hydronephrosis in children
por: de Bessa Jr, Jose, et al.
Publicado: (2018)

Dosing Oncology Therapeutics in Combination Therapy for Renal Dysfunction: The University of California San Diego Study of Personalized Cancer Therapy to Determine Response and Toxicity (UCSD-PREDICT) Experience
por: Nikanjam, Mina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t96s2kgotdqlamsiam6d96ti1p