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Hedgehog-GLI mediated control of renal formation and malformation

CAKUT is the leading cause of end-stage kidney disease in children and comprises a broad spectrum of phenotypic abnormalities in kidney and ureter development. Molecular mechanisms underlying the pathogenesis of CAKUT have been elucidated in genetic models, predominantly in the mouse, a paradigm for...

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Detalles Bibliográficos
Autores principales: Greenberg, Dina, D’Cruz, Robert, Lacanlale, Jon L., Rowan, Christopher J., Rosenblum, Norman D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479618/
https://www.ncbi.nlm.nih.gov/pubmed/37675356
http://dx.doi.org/10.3389/fneph.2023.1176347