The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors

BACKGROUND: High-grade gliomas (HGG) are aggressive brain tumors associated with short median patient survival and limited response to therapies, driving the need to develop tools to improve patient outcomes. Patient-derived xenograft (PDX) models, such as mouse PDX, have emerged as potential Avatar...

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Detalles Bibliográficos
Autores principales: Charbonneau, Martine, Harper, Kelly, Brochu-Gaudreau, Karine, Perreault, Alexis, Roy, Laurent-Olivier, Lucien, Fabrice, Tian, Shulan, Fortin, David, Dubois, Claire M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479744/
https://www.ncbi.nlm.nih.gov/pubmed/36821432
http://dx.doi.org/10.1093/neuonc/noad047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479744/
https://www.ncbi.nlm.nih.gov/pubmed/36821432
http://dx.doi.org/10.1093/neuonc/noad047

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