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Fingolimod Modulates the Gene Expression of Proteins Engaged in Inflammation and Amyloid-Beta Metabolism and Improves Exploratory and Anxiety-Like Behavior in Obese Mice

Obesity is considered a risk factor for type 2 diabetes mellitus, which has become one of the most important health problems, and is also linked with memory and executive function decline. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that regulates cell death/survival and the inflammato...

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Detalles Bibliográficos
Autores principales: Wencel, P. L., Blecharz-Klin, K., Piechal, A., Pyrzanowska, J., Mirowska-Guzel, D., Strosznajder, R. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480137/
https://www.ncbi.nlm.nih.gov/pubmed/37432552
http://dx.doi.org/10.1007/s13311-023-01403-2