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Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency
A molecular and functional link between neurotrophin signaling and cerebellar foliation is lacking. Here we show that constitutive knockout of two homologous genes encoding the RNA binding protein RBM4 results in foliation defects at cerebellar lobules VI–VII and delayed motor learning in mice. More...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480162/ https://www.ncbi.nlm.nih.gov/pubmed/37670183 http://dx.doi.org/10.1038/s42003-023-05294-z |