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Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis

Recent blood transcriptomic analysis of rhodesiense sleeping sickness patients has revealed that neutrophil signature genes and activation markers constitute the top indicators of trypanosomiasis-associated inflammation. Here, we show that Trypanosoma brucei infection results in expansion and differ...

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Detalles Bibliográficos
Autores principales: Pham, Hien Thi Thu, Magez, Stefan, Choi, Boyoon, Baatar, Bolortsetseg, Jung, Joohee, Radwanska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480172/
https://www.ncbi.nlm.nih.gov/pubmed/37669943
http://dx.doi.org/10.1038/s41467-023-41089-w