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Inhibition of ACSL4 ameliorates tubular ferroptotic cell death and protects against fibrotic kidney disease

Ferroptosis is a recently recognized form of regulated cell death, characterized by iron-dependent accumulation of lipid peroxidation. Ample evidence has depicted that ferroptosis plays an essential role in the cause or consequence of human diseases, including cancer, neurodegenerative disease and a...

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Detalles Bibliográficos
Autores principales: Dai, Yue, Chen, Yuting, Mo, Dexiameng, Jin, Rui, Huang, Yi, Zhang, Le, Zhang, Cuntai, Gao, Hongyu, Yan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480178/
https://www.ncbi.nlm.nih.gov/pubmed/37670055
http://dx.doi.org/10.1038/s42003-023-05272-5