Control of intracellular pH and bicarbonate by CO(2) diffusion into human sperm

The reaction of CO(2) with H(2)O to form bicarbonate (HCO(3)(−)) and H(+) controls sperm motility and fertilization via HCO(3)(−)-stimulated cAMP synthesis. A complex network of signaling proteins participates in this reaction. Here, we identify key players that regulate intracellular pH (pH(i)) and...

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Detalles Bibliográficos
Autores principales: Grahn, Elena, Kaufmann, Svenja V., Askarova, Malika, Ninov, Momchil, Welp, Luisa M., Berger, Thomas K., Urlaub, Henning, Kaupp, U.Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480191/
https://www.ncbi.nlm.nih.gov/pubmed/37669933
http://dx.doi.org/10.1038/s41467-023-40855-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480191/
https://www.ncbi.nlm.nih.gov/pubmed/37669933
http://dx.doi.org/10.1038/s41467-023-40855-0

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