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Control of intracellular pH and bicarbonate by CO(2) diffusion into human sperm
The reaction of CO(2) with H(2)O to form bicarbonate (HCO(3)(−)) and H(+) controls sperm motility and fertilization via HCO(3)(−)-stimulated cAMP synthesis. A complex network of signaling proteins participates in this reaction. Here, we identify key players that regulate intracellular pH (pH(i)) and...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480191/ https://www.ncbi.nlm.nih.gov/pubmed/37669933 http://dx.doi.org/10.1038/s41467-023-40855-0 |