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Human myofibroblasts increase the arrhythmogenic potential of human induced pluripotent stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have the potential to remuscularize infarcted hearts but their arrhythmogenicity remains an obstacle to safe transplantation. Myofibroblasts are the predominant cell-type in the infarcted myocardium but their impact on transplant...

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Detalles Bibliográficos
Autores principales: Johnson, Robert D., Lei, Ming, McVey, John H., Camelliti, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480244/
https://www.ncbi.nlm.nih.gov/pubmed/37668685
http://dx.doi.org/10.1007/s00018-023-04924-3