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Acute myeloid leukemia with concurrent NPM1 and RUNX1 mutations

NPM1 mutation, as a founding genetic event, cooperates with other gene mutations, such as DNMT3A and FLT3, to promote the development of acute myeloid leukemia. NPM1 mutation, however, has been reported to be mutually exclusive with RUNX1 mutation in acute myeloid leukemia cases. In this study, we a...

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Detalles Bibliográficos
Autores principales: Zuo, Zhuang, Medeiros, L. Jeffrey, Yin, C. Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480299/
https://www.ncbi.nlm.nih.gov/pubmed/37680325
http://dx.doi.org/10.1016/j.lrr.2023.100385