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IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
Th9 cells are powerful effector T cells for cancer immunotherapy. However, the underlying antitumor mechanism of Th9 cells still needs to be further elucidated. Here, we show that Th9 cells express high levels of not only IL-9, but also IL-24. We found that knockout of Il24 gene in Th9 cells promote...
Autores principales: | Chen, Jintong, Zhang, Yunwei, Zhang, Hua, Zhang, Mingyue, Dong, He, Qin, Tianxue, Gao, Sujun, Wang, Siqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480301/ https://www.ncbi.nlm.nih.gov/pubmed/37680459 http://dx.doi.org/10.1016/j.isci.2023.107531 |
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