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A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities

Recent genomic studies reported that 90 to 95% of human genes can undergo alternative splicing, by which multiple isoforms of proteins are synthesized. However, the functional consequences of most of the isoforms are largely unknown. Here, we report a novel alternatively spliced isoform of nonmuscle...

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Detalles Bibliográficos
Autores principales: Das, Samprita, Mallick, Ditipriya, Sarkar, Sourav, Billington, Neil, Sellers, James R., Jana, Siddhartha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480317/
https://www.ncbi.nlm.nih.gov/pubmed/37562567
http://dx.doi.org/10.1016/j.jbc.2023.105143