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In vivo cortical glutathione response to oral fumarate therapy in relapsing-remitting multiple sclerosis: A single-arm open-label phase IV trial using 7-Tesla (1)H MRS

BACKGROUND: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy ((1)H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as a disease-modifying therapy for multiple scl...

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Detalles Bibliográficos
Autores principales: Juchem, Christoph, Swanberg, Kelley M., Prinsen, Hetty, Pelletier, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480324/
https://www.ncbi.nlm.nih.gov/pubmed/37651844
http://dx.doi.org/10.1016/j.nicl.2023.103495