Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores

Viral sensing in myeloid cells involves inflammasome activation leading to gasdermin pore formation, cytokine release, and cell death. However, less is known about viral sensing in barrier epithelial cells, which are critical to the innate immune response to RNA viruses. Here, we show that poly(I:C)...

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Detalles Bibliográficos
Autores principales: Guy, Coralie, Baran, Marcin, Ribó-Molina, Pau, van den Hoogen, Bernadette G., Bowie, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480325/
https://www.ncbi.nlm.nih.gov/pubmed/37680489
http://dx.doi.org/10.1016/j.isci.2023.107698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480325/
https://www.ncbi.nlm.nih.gov/pubmed/37680489
http://dx.doi.org/10.1016/j.isci.2023.107698

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