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Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores
Viral sensing in myeloid cells involves inflammasome activation leading to gasdermin pore formation, cytokine release, and cell death. However, less is known about viral sensing in barrier epithelial cells, which are critical to the innate immune response to RNA viruses. Here, we show that poly(I:C)...
Autores principales: | Guy, Coralie, Baran, Marcin, Ribó-Molina, Pau, van den Hoogen, Bernadette G., Bowie, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480325/ https://www.ncbi.nlm.nih.gov/pubmed/37680489 http://dx.doi.org/10.1016/j.isci.2023.107698 |
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