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A Phase 1b, Open-Label Study to Evaluate the Safety and Tolerability of the Putative Remyelinating Agent, Liothyronine, in Individuals with MS

Thyroid hormones are essential during developmental myelination and may play a direct role in remyelination and repair in the adult central nervous system by promoting the differentiation of oligodendrocyte precursor cells into mature oligodendrocytes. Since tri-iodothyronine (T3) is believed to med...

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Detalles Bibliográficos
Autores principales: Newsome, Scott D., Tian, Fan, Shoemaker, Thomas, Fitzgerald, Kathryn C., Cassard, Sandra D., Fiol, Julie, Snoops, Sarah, Cooper, David S., Mammen, Jennifer S. R., Bhargava, Pavan, Mowry, Ellen M., Calabresi, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480368/
https://www.ncbi.nlm.nih.gov/pubmed/37460763
http://dx.doi.org/10.1007/s13311-023-01402-3