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A Phase 1b, Open-Label Study to Evaluate the Safety and Tolerability of the Putative Remyelinating Agent, Liothyronine, in Individuals with MS
Thyroid hormones are essential during developmental myelination and may play a direct role in remyelination and repair in the adult central nervous system by promoting the differentiation of oligodendrocyte precursor cells into mature oligodendrocytes. Since tri-iodothyronine (T3) is believed to med...
Autores principales: | Newsome, Scott D., Tian, Fan, Shoemaker, Thomas, Fitzgerald, Kathryn C., Cassard, Sandra D., Fiol, Julie, Snoops, Sarah, Cooper, David S., Mammen, Jennifer S. R., Bhargava, Pavan, Mowry, Ellen M., Calabresi, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480368/ https://www.ncbi.nlm.nih.gov/pubmed/37460763 http://dx.doi.org/10.1007/s13311-023-01402-3 |
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