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Losartan Reduces Remodeling and Apoptosis in an Adriamycin-Induced Cardiomyopathy Rat Model

BACKGROUND: The use of Adriamycin (ADR), also known as doxorubicin, as a chemotherapy agent is limited by its detrimental adverse effects, especially cardiotoxicity. Recent studies have emphasized the crucial role of angiotensin II (Ang-II) in the development of ADR-induced cardiomyopathy. This stud...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon A, Kim, Kwan Chang, Lee, Hyeryon, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480395/
https://www.ncbi.nlm.nih.gov/pubmed/37574884
http://dx.doi.org/10.5090/jcs.23.044