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A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

Intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but mechanisms regulating ISCs and their niche after damage remain poorly understood. Utilizing radiation injury to model intestinal pathology, we report here that the Interleukin-33 (IL-33)/ST2 axis, an immunomodulatory...

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Detalles Bibliográficos
Autores principales: Calafiore, Marco, Fu, Ya-Yuan, Vinci, Paola, Arnhold, Viktor, Chang, Winston Y., Jansen, Suze A., Egorova, Anastasiya, Takashima, Shuichiro, Kuttiyara, Jason, Ito, Takahiro, Serody, Jonathan, Nakae, Susumu, Turnquist, Heth, van Es, Johan, Clevers, Hans, Lindemans, Caroline A., Blazar, Bruce R., Hanash, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480426/
https://www.ncbi.nlm.nih.gov/pubmed/37669929
http://dx.doi.org/10.1038/s41467-023-40993-5