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A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury
Intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but mechanisms regulating ISCs and their niche after damage remain poorly understood. Utilizing radiation injury to model intestinal pathology, we report here that the Interleukin-33 (IL-33)/ST2 axis, an immunomodulatory...
Autores principales: | Calafiore, Marco, Fu, Ya-Yuan, Vinci, Paola, Arnhold, Viktor, Chang, Winston Y., Jansen, Suze A., Egorova, Anastasiya, Takashima, Shuichiro, Kuttiyara, Jason, Ito, Takahiro, Serody, Jonathan, Nakae, Susumu, Turnquist, Heth, van Es, Johan, Clevers, Hans, Lindemans, Caroline A., Blazar, Bruce R., Hanash, Alan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480426/ https://www.ncbi.nlm.nih.gov/pubmed/37669929 http://dx.doi.org/10.1038/s41467-023-40993-5 |
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