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Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is a serious public health problem due to its high incidence and metastatic potential. It may progress from actinic keratosis (AK), a precancerous lesion, or the in situ carcinoma, Bowen’s disease (BD). During this progression, malignant keratinocytes activat...

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Detalles Bibliográficos
Autores principales: Schütz, Sabrina, Solé-Boldo, Llorenç, Lucena-Porcel, Carlota, Hoffmann, Jochen, Brobeil, Alexander, Lonsdorf, Anke S., Rodríguez-Paredes, Manuel, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480447/
https://www.ncbi.nlm.nih.gov/pubmed/37669956
http://dx.doi.org/10.1038/s41467-023-41141-9