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Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma
Cutaneous squamous cell carcinoma (cSCC) is a serious public health problem due to its high incidence and metastatic potential. It may progress from actinic keratosis (AK), a precancerous lesion, or the in situ carcinoma, Bowen’s disease (BD). During this progression, malignant keratinocytes activat...
Autores principales: | Schütz, Sabrina, Solé-Boldo, Llorenç, Lucena-Porcel, Carlota, Hoffmann, Jochen, Brobeil, Alexander, Lonsdorf, Anke S., Rodríguez-Paredes, Manuel, Lyko, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480447/ https://www.ncbi.nlm.nih.gov/pubmed/37669956 http://dx.doi.org/10.1038/s41467-023-41141-9 |
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